Most standard multivitamins are formulated to prevent basic nutrient deficiencies — they’re broad, generalized, and optimized for a long ingredient list rather than meaningful metabolic support. Noom Metabolic is built differently. It’s not just a multivitamin. It’s a clinician-guided, science-backed formula featuring a unique blend of metabolically active ingredients — like Dihydroberberine (GlucoVantage®), Alpha-Lipoic Acid, and Chromium — chosen specifically to support blood sugar regulation, insulin sensitivity, and inflammation reduction. These ingredients are not found in standard multivitamins.

The system is also sex-specific, recognizing that men and women have different metabolic needs. And with AM and PM formulas designed around your body’s natural rhythms, you get morning energy and metabolic activation when you need it, and overnight recovery and metabolic reset while you sleep.

Noom Metabolic includes many of the foundational vitamins and minerals 
found in a standard multivitamin — so for many people, it can replace it. And it goes further: beyond foundational nutrition, it delivers a unique blend of metabolically active ingredients specifically chosen to support metabolism, energy, and blood sugar.

If you currently take other vitamins or supplements, it’s worth a quick check with your healthcare provider before combining or replacing products — more isn’t always better, and it’s easy to double up on certain nutrients, particularly fat-soluble vitamins like Vitamin A and D, without realizing it.

The Women’s AM and PM formulas are designed around the specific nutritional needs and metabolic patterns common in women:

Folate as L-5-MTHF (400 mcg DFE) 

Delivered in its active, bioavailable form to support methylation, cardiovascular health, and homocysteine regulation.

Calcium (Mineralized Algae, 150 mg in PM)
Supports bone density, which is a heightened concern for women given higher lifetime osteoporosis risk.

Boron (3 mg in PM)
Supports estrogen and testosterone balance.

Women’s AM focus
Energy, metabolism, cognitive function, and stress resilience.

Women’s PM focus
Recovery, metabolic regulation, hormone balance, and inflammation control.

The Men’s AM and PM formulas are built to support testosterone, prostate health, and metabolic vitality:

Zinc (11 mg in AM) and Vitamin D3 (2,000 IU in AM)
Both have evidence supporting testosterone production and immune function.

Lycopene (6 mg in AM)
Supports prostate health and cardiovascular function, including healthy LDL levels

DIM — Diindolylmethane (50 mg in PM)
Anti-inflammatory properties and supports hormone balance.

Men’s AM focus
Energy, metabolism, and testosterone support.

Men’s PM focus
Recovery, hormonal balance, and inflammation reduction.

The AM and PM formulas are intentionally different and timed to align with your body’s natural daily rhythms. The AM formula is rich in B-vitamins, Vitamin D3, and metabolic activators like Dihydroberberine and Alpha-Lipoic Acid — all of which support energy production, focus, and metabolic function during your active hours. The PM formula emphasizes Magnesium (which supports relaxation and blood sugar regulation overnight) and additional Dihydroberberine and ALA to support overnight metabolic recovery. Splitting the dose across AM and PM also allows for higher total daily amounts of key active ingredients while maintaining tolerability.

Like all dietary supplements, Noom Metabolic is not FDA-approved — dietary supplements don’t require FDA approval before going to market. What sets Noom Metabolic apart is that every ingredient is selected with the same evidence-first approach that guides every Noom program. Each has a clinical reason to be there, included at meaningful doses — not just label-claim amounts:

Dihydroberberine (GlucoVantage®) — A more easily absorbed form of natural berberine, helps support healthy blood sugar and cholesterol within normal limits

Alpha-Lipoic Acid — studied for antioxidant support and metabolic function

Chromium — studied for its role in supporting healthy blood sugar balance

Vitamin D3 & Vitamin K2 — well-established research bases supporting metabolic, cardiovascular, and bone health

Folate (L-5-MTHF) — the active form, associated with cardiovascular health and normal cellular function.

Noom Metabolic is gluten-free, dairy-free, non-GMO, and contains no artificial colors or flavors. The PM supplement is vegan, but the AM supplement is not because it contains Vitamin D3 (Cholecalciferol), which is derived from lanolin and may not be suitable for strict vegans.

Yes. These supplements are designed to complement a GLP-1 treatment plan. Several ingredients — including Dihydroberberine, Alpha-Lipoic Acid, Chromium Picolinate, and Magnesium — support metabolic pathways that GLP-1 medications also target, such as blood sugar regulation and insulin sensitivity. Because these ingredients may have additive effects on glucose levels, we recommend informing your Noom Med provider or prescribing physician before adding them to your regimen, particularly if you are also on insulin or other glucose-lowering agents.

Noom Metabolic should not be taken while pregnant or breastfeeding. It is always recommended to consult your doctor before starting a supplement.

Most ingredients in these supplements are well-tolerated, but certain ingredients may interact with specific medications. Notable considerations include:

Alpha-Lipoic Acid and Dihydroberberine may enhance the glucose-lowering effects of diabetes medications, which could increase the risk of hypoglycemia.

Vitamin K2 (MK-7) may interact with blood thinners such as warfarin — patients on anticoagulant therapy should consult their provider.

Chromium Picolinate may interact with insulin or other diabetes medications.

Kelp-derived Iodine (in the PM formula) may affect thyroid medication dosing in individuals with thyroid conditions.

We strongly recommend people review their full medication and supplement list with their healthcare provider or pharmacist before starting.

Several ingredients in these supplements are specifically included to support metabolic and thyroid function, which means they can have meaningful physiological effects in individuals with pre-existing conditions.

Noom Metabolic may not be a good fit for individuals with the following 
pre-existing conditions:

Diabetes / blood sugar conditions
Dihydroberberine, Alpha-Lipoic Acid, Chromium Picolinate, and Magnesium all influence glucose regulation and may interact with diabetes medications. Close provider monitoring is recommended.

Thyroid conditions
Selenium and kelp-derived Iodine support thyroid function but could affect thyroid hormone levels or interact with medications for hyper- or hypothyroidism.

Cardiovascular conditions / anticoagulant therapy

Vitamin K2 (MK-7) may interfere with warfarin or other blood thinners.

Please consult your healthcare provider before starting these supplements if you have any chronic health conditions or are taking prescription medications.

We recommend taking both the AM and PM supplements with food. Several ingredients — including Vitamins A, D, and K2 (fat-soluble) and Alpha-Lipoic Acid — are better absorbed when consumed alongside a meal that contains some fat. Taking supplements with food can also reduce the likelihood of gastrointestinal discomfort, which some individuals may experience with ingredients like Dihydroberberine or ALA on an empty stomach.

If you miss a dose, simply skip it and resume your regular schedule with your next meal. Do not double up to compensate for a missed dose. Consistency over time is what matters most — occasional missed doses are unlikely to significantly impact your results.

Store your supplements in a cool, dry place away from direct sunlight and excess moisture. Avoid storing them in high-humidity environments such as bathrooms or near kitchen sinks. Keep out of reach of children. Refrigeration is not required unless otherwise stated on the product label.

Each bottle is labeled with an expiration date. For best potency and efficacy, use the supplements before the printed expiration date. Supplements stored properly in a cool, dry environment are generally formulated to maintain their potency through that date. Do not use supplements that appear discolored, have an unusual odor, or are past their expiration date.